Sierra QMS

Review of Sierra QMS Software: system overview, features, price and cost information. Get free demos and compare to similar programs.

Overview

About Sierra QMS

Sierra QMS is a highly configurable and customizable quality management system (QMS) built specifically for healthcare and life sciences industry. It leverages agile technology and automation capabilities to ease the burdens of regulatory compliance, lower compliance costs, and accelerate time to market. Due to its customizable nature, Sierra QMS is designed for any business size at any life cycle stage. The system supports you with managing your documents, trainings, non-conformances, CAPAs, and audit events to show compliance with GxP validation and verification processes and 21 CFR Part 11 requirements. Sierra QMS also automates the publishing of validation artifacts (such as user requirements, functional specifications, code review reports, etc.) from other applications. This platform is designed for biotech, digital health, pharmaceutical, and clinical research companies looking for an agile and efficient approach to quality and compliance. Create and track non-conformance and CAPAs with deep linking to related policies, audit events, training, and other related items. Utilize the systems clean and customized Dashboard to quickly monitor non-conformance and CAPA status. Appl...

Sierra QMS Screenshots

Sierra QMS Features

Features of Sierra QMS
Change Management
Complaint Management
Corrective and Preventive Actions (CAPA)
Defect Tracking
Document Management
Electronic Signature
Incident Management
Quality Control
Risk Management
Task Management

Sierra QMS Integrations

Bitbucket logo
Bitbucket
GitHub logo
GitHub
Jira logo
Jira
TestRail logo
TestRail
GitLab logo
GitLab
Trello logo
Trello

Customer Reviews

See why people love Sierra QMS

5 Star
90%
4 Star
10%
3 Star
0%
2 Star
0%
1 Star
0%

Amber N.

Verified User

Medical Devices · 2-10 employees

Used weekly for less than 12 months
Dec 22, 2025

New to QMS

Great company, excellent expertise and would recommend 100%.

What they liked
  • We reviewed 7 QMS products and Sierra QMS seemed to be the most intuitive
  • It also had better functionality for software heavy products for integration to show traceability - many other QMS products don't have this
Room for improvement

That the user needs cannot be rearranged and that they are listed in a chronological order

Why they chose it

"Greenlight Guru was too pushy and it was overpriced for what we needed - a lot of add on costs."

Ashoi P.

Verified User

Computer Software · 11-50 employees

Used weekly for less than 12 months
Dec 22, 2025

Highly capable Quality Management System

Verified reviewer

What they liked
  • The QMS is very easy to use and navigate
  • The highly-configurable options allow the QMS administrator to create complex workflows with automation rules to handle the organization's business processes
  • From an end-user perspective, it's really easy to follow along the workflows when completing change orders or CAPAs
Room for improvement
  • The QMS could use some more robust data querying and reporting features
Why they chose it

"Cheaper and easier to use, while supporting greater integration options with other software tools"

Ryan E.

Verified User

Computer Software · 11-50 employees

Used weekly for free trial
Dec 22, 2025

Sierra QMS

Verified reviewer

What they liked

I found the training programs very helpful, made it very simple to setup new training plans and to assign the teams that would be participating, as well as monitor what trainings our teams had finished already

Room for improvement

I thought the help section could be improved, would be nice to possible see a list of common questions to improve the initial learning curve of the product

Michael P.

Verified User

Health, Wellness and Fitness · 2-10 employees

Used weekly for less than 12 months
Dec 22, 2025

Opio QMS review

It's been a great overall experience with Sierra as we've changed direction a couple times now and they are adaptive and understanding of our needs as we narrow in on our path to market.

What they liked
  • The software ease of use and intuitive layout made sense
Room for improvement

Since we were building our QMS from scratch, perhaps access to other example QMS documents/layouts would be helpful

Why they chose it

"Simply to use at a better cost point with available help to build our system from scratch."

Carrie B.

Verified User

Medical Devices · 11-50 employees

Used daily for less than 6 months
Dec 22, 2025

Sierra QMS for Startup Medical Device Company

Sierra is so much more than a document retention system. There is a lot of built in functionality. We can automate the Design Trace Matrix (i.e. DI/DO/DVV), Hazard Trace Matrix, and Tracking of Equipment PM/CAL and input CAPAs, Complaints, Nonconformances, etc. It is great how you can reference items to other items within the QMS.

What they liked
  • Sierra QMS is Highly configurable
  • We are able to customize it to our needs
  • If it is not built in, it can be built
  • Sierra developed a Risk Analysis module for us so we can track risks for CAPAs, Complaints, non conformances, etc
  • With their platform, new modules are pretty quick to deploy
  • You can essentially automate any kind of form that you want
  • It has more functionality than the competitors
  • For example, there are built in Modules for Design and Hazard traceability
  • Imagine no more complicated spreadsheets to maintain
  • I like the Supplier Management module
  • You can email a link to a supplier and they can populate their supplier evaluation survey within Sierra QMS
  • I also like the CAPA module as you can customize the electronic forms and workflows
  • It is very easy to use as an admin and as an average user
  • It takes very little training for a new user to get started due to the intuitive UI
  • We found the pricing to be simple and competitive
Room for improvement
  • I wish I could export the raw data from the QMS so I can make ad hoc reports
  • I hear this is coming soon though
  • It would be nice if you could collaborate on documents undergoing a change order within the software
Why they chose it

"Sierra QMS was more configurable, more affordable, and had a more intuitive user interface."

Emily M.

Verified User

Hospital & Health Care · 11-50 employees

Used weekly for more than 2 years
May 28, 2026

QMS for Healthcare Review

Overall a great system! It has really helped to automate our compliance processes and decrease the amount of manual validation work for our teams. It has made it easier for our product and engineering teams to align with our QA/RA teams.

What they liked
  • It's pretty customizable
  • The Sierra Labs team worked with us to create custom templates and workflows, and made the transition to a new system easy
  • The interface is user-friendly and the dashboard provides an up to date view of all of our tasks and assignments
Room for improvement
  • We originally wanted to integrate the QMS with a project management software other than Jira, but the QMS integrates so well with Jira that we ended up switching to that system
  • But more integration capabilities would be great for future production
Switched From

Sierra QMS has higher customization capabilities and is more user friendly.

Kwame U.

Verified User

Medical Devices · Self-Employed

Used weekly for less than 2 years
May 28, 2026

Sierra Labs Ease of Use

Verified reviewer

What they liked
  • The Sierra Labs environment is extremely intuitive and easy to use
  • The main data entry points are easy to find and the approval process is frictionless
  • I appreciate the real time updating and how tightly the tool allows a development team to map to ISO 13485 and the USFDA QSR
  • Some other aspects are the robust modules and dashboard that is easy to understand
  • I use the Sierra Labs QMS with my clients and plan to move them more in the future
Room for improvement

Email/Notification settings need to be configurable, but it is likely an easy update

Eric R.

Verified User

Information Technology and Services · 2-10 employees

Used weekly for less than 12 months
May 28, 2026

Most straightforward & simple QMS I've Used

The Sierra team was very helpful and communicative with the process of getting us set up and our environment configured. We had a consistent point of contact who was proactive at getting us set up as quickly as possible while explaining the best practices and tradeoffs along the way.

What they liked
  • I appreciate how straightforward Sierra QMS is to use and understand
  • I have used other QMS solutions and I found them to be a labyrinth of business logic that was very difficult to navigate, configure, or learn how to use effectively
  • The document control and versioning is very simple to work with and reviewing documents in the browser is great which saves the effort of having to download for review
Room for improvement

While a very strong entry in usability and design, there's always room for improvement to simplify the interface even further

Ian M.

Verified User

Medical Devices · 2-10 employees

Used weekly for less than 12 months
May 28, 2026

Great Product for a Great Price

Verified reviewer

What they liked
  • It's highly intuitive and helps us manage multiple portions of our business
  • As a SaMD company, we have to simultaneously keep track of design controls for our own records, but also for incoming team members
  • We also needed a product that could enable seamless review of updates to key process all while remaining in compliance with regulations
Room for improvement
  • I'd like a way to quickly download all of my process documents without having to go into each one to export
  • There may already be an easy way to do this that I haven't discovered yet

Evan T.

Verified User

Medical Devices · 11-50 employees

Used monthly for less than 12 months
May 28, 2026

Sierra QMS offers simple workflows.

So far, we have enjoyed working with Sierra to deploy quality management systems in medical device companies--the support and knowledge that come with Sierra's product makes it easy.

What they liked
  • We find Sierra's eQMS offering easy to use with our clients
  • It helps simplify workflows and quality engineering for medical device development
Room for improvement
  • We are uncertain about the ease of Part 11 validation

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Sierra QMS

Sierra QMS

4.9
Pricing
Pricing available upon request

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